Docetaxel Followed by Radical Prostatectomy in Patients With High Risk Localized Prostate Cancer
Status:
Completed
Trial end date:
2011-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to determine if the combination of chemotherapy and
hormone therapy is safe and helpful for patients who plan to have their high-risk prostate
cancer surgically removed. Some physicians believe that patients with high risk cancer that
is located in one area, may have an early but small spread of the cancer outside of the
prostate, and perhaps even to distant organs. Therefore, better treatments for the entire
body are needed to improve the ability of surgery or other local therapies to cure prostate
cancer. Since chemotherapy is beginning to demonstrate increasing activity in advanced
prostate cancer patients, it is possible that using chemotherapy combined with hormonal
therapy earlier in the course of localized but high risk patients might improve the outcomes
for these patients.