Dobutamine for Management of Surgical Patients with Septic Shock
Status:
RECRUITING
Trial end date:
2027-04-30
Target enrollment:
Participant gender:
Summary
Septic shock is the last and most severe stage of sepsis and is defined by extremely low blood pressure, despite lots of intravenous fluids. The incidence of septic shock related cardiomyopathy was 10% to 70%. Besides, general anesthesia will inhibit the sympathetic nervous system, reduce myocardial contractility and aggravate cardiac dysfunction. No randomized controlled trials have yet explore the effects of dobutamine on clinical outcomes for patients with septic shock undergoing surgery under general anesthesia.
Phase:
NA
Details
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Collaborators:
Affiliated Hospital of Guangdong Medical University Affiliated Hospital of Jiaxing University Anqing People's Hospital of Anhui Medical University Bijie Hospital of Zhejiang Provincial People's Hospital Central Hospital of Heng Yang First Affiliated Hospital of Shenzhen University First Affiliated Hospital of Xinjiang Medical University Fujian Provincial Hospital Fuyang Hospital of Anhui Medical University Guizhou Provincial People's Hospital Henan Provincial People's Hospital Huaibei Peolple's Hospital Lishui Country People's Hospital Ningbo No. 1 Hospital Ningbo No.2 Hospital People's Hospital of Xinjiang Uygur Autonomous Region Red Cross Hospital, Hangzhou, China Renmin Hospital of Wuhan University Southwest Hospital, China Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University The Central Hospital of Lishui City The First Affiliated Hospital of Anhui Medical University The First Affiliated Hospital of Shihezi University Medical College The First Affiliated Hospital of Soochow University The First Affiliated Hospital of University of South China The First Affiliated Hospital of Zhengzhou University The First Clinical College of Harbin University The First People's Hospital of Zunyi The Hospital of Suixi County The Second Hospital of Hebei Medical University The Second Hospital University of South China Tianjin Medical University General Hospital Tongji Hospital Union hospital of Fujian Medical University Weifang People's Hospital Weihai Municipal Hospital Wenzhou people's hospital，zhejiang province,China Wuhan Third Hospital Zhejiang Cancer Hospital Zhejiang Provincial People’s Hospital Zhejiang Provincial Tongde Hospital Zhujiang Hospital Zunyi Medical College