Do Oral Contraceptives Protect Against ACL Injuries in Female Athletes

• Status: Not yet recruiting
• Trial end date: 2022-08-31
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this research study is to examine the impact of one type of commonly used birth control pill on blood levels of relaxin and measure changes in knee movement to determine whether there are changes in joint instability (indicating the knee is less stable) that may predispose female athletes to injury. Women not on hormonal birth control will also be enrolled to analyze differences between athletes on and not on birth control and to evaluate typical relaxin levels and knee laxity when birth control pills are not used.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Cedars-Sinai Medical Center
• Treatments: Contraceptive Agents; Contraceptives, Oral; Contraceptives, Oral, Combined

Criteria

Inclusion Criteria:

• Female

• 18 years of age or older

• Currently playing basketball, soccer, or volleyball at Loyola Marymount or Pepperdine

• If not currently on COC, regular menstrual cycle occurring every 21-35 days

Exclusion Criteria:

• Previous ACL injury

• Underlying neuromuscular disease

• Medical contraindication to COC use

• History of pregnancy

• Desire to conceive in the next year