Overview

Do Benzodiazepines Improve the Outcome of Mechanical Physiotherapy for Lumbar Disk Prolapse

Status:
Completed
Trial end date:
2007-04-01
Target enrollment:
0
Participant gender:
All
Summary
Sixty patients were randomized to receive either placebo or diazepam in addition to mechanical physiotherapy and analgesics for the first 7 days of conservative treatment of clinically and radiologically confirmed lumbar disk prolapse
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University Hospital Tuebingen
Criteria
Inclusion Criteria:

- sciatica without or with neurological deficit attributable to lumbar disc prolapse

- CT or MRI confirmation of lumbar disc prolapse

- informed consent

Exclusion Criteria:

- bladder or bowel disturbance

- acute (< 24 h) development of paresis grade 1 or plegia

- taken benzodiazepines for more than 2 weeks

- history of benzodiazepine intolerance

- prior surgery for disc prolapse, or prior trauma to the vertrebral column