Overview

Do Acid Sensing Ion Channels Contribute to Heartburn?

Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to learn about whether treating the esophagus with amiloride reduces either the frequency or the time to onset of acid-induced heartburn in patients with nonerosive reflux disease. In particular, we are looking at people who have either had complete relief while using a Proton Pump Inhibitor (PPI) or who have only had some relief of symptoms while on a PPI.
Phase:
Phase 1
Details
Lead Sponsor:
University of North Carolina, Chapel Hill
Treatments:
Amiloride