Diurnal Variation of Exogenous Peptides (Endogenous Insulin Jurgita II)
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
This is an exploratory trial with two cross-over arms investigating pharmacokinetic profiles
of endogenous and exogenous insulin in type 2 diabetes mellitus patients treated with
continuous subcutaneous Insulin Aspart infusion and combined with or without intravenous
glucose infusion. The order of treatment session will be randomised.
Hypotheses:
1. Secretion of endogenous insulin depends on exogenous insulin supply
2. Secretion of endogenous insulin is depends on plasma glucose levels