Diuretics In the Management of Essential Hypertension (DIME) Study
Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
The purpose of DIME is to evaluate the safety (i.e. new onset of diabetes and other metabolic
adverse events), efficacy and cost-effectiveness of antihypertensive treatment with low dose
diuretics. The researchers' hypothesis is that use of low dose thiazide diuretics is
metabolically safe when used with other appropriate antihypertensives, effective in reduction
of blood pressure and cheaper than treatment without diuretics. Therefore, this study is an
equivalence trial.