Overview

Diuretic Strategies in Acute Heart Failure Patients at High Risk for Diuretic Resistance

Status:
Recruiting
Trial end date:
2025-12-31
Target enrollment:
Participant gender:
Summary
The P-VALUE-AHF trial is a multicenter, randomized, open-label, parallel-group trial on the diuretic and decongestive effects of different diuretic escalation strategies in patients with acute heart failure and diuretic resistance. The main aims are - to compare the diuretic efficacy of three therapeutic strategies in patients with acute heart failure and diuretic resistance. - to assess the improvement in clinical congestion and to compare the symptom-relief among the different treatment regimens
Phase:
Phase 4
Details
Lead Sponsor:
Stadtspital Zürich
Collaborator:
Ospedale Regionale di Lugano
Treatments:
Acetazolamide
Furosemide
Metolazone