Disulfiram (Antabuse®) is a well-tolerated, cheap, generic drug that has been in use since
the 1950s to treat alcoholism. There is now an increasing amount of independent preclinical
data to support disulfiram as an anticancer agent. The potency of disulfiram as an anticancer
agent seems strengthened by copper.
The investigators aim is to investigate disulfiram and copper-supplement as add-on treatment
in glioblastoma patients with recurrence receiving alkylating chemotherapy.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Sahlgrenska University Hospital, Sweden
Collaborators:
Karolinska University Hospital Lund University Hospital Region Örebro County Ryhov County Hospital St. Olavs Hospital University Hospital, Linkoeping Uppsala University Hospital