Overview

Direct Peritoneal Resuscitation Plus Conventional Resuscitation

Status:
Withdrawn
Trial end date:
2014-05-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to find out if direct peritoneal resuscitation (DPR) (putting a sugar solution into the abdominal cavity) helps blood flow through vital organs in the body that may suffer from low blood flow due to surgery. We will also try to find out if the DPR will help patients recover faster from liver surgery. Lastly, this study will also try to find if direct peritoneal resuscitation decreases levels of signaling chemicals in the blood called 'cytokines' and a protein called high-mobility group protein 1, which is known to cause tissue damage.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Louisville
Criteria
Inclusion Criteria:

- Colorectal cancer

- Scheduled for liver resection

- 18 to 75

Exclusion Criteria:

- Chronic renal failure

- Cirrhosis

- Congestive heart failure

- Requiring portal venous embolization prior to resection

- Pregnant or nursing