Overview

Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer

Status:
Completed
Trial end date:
2020-11-18
Target enrollment:
Participant gender:
Summary
The overarching objective of the study is to determine the effectiveness of LMWH/ warfarin vs. DOAC anticoagulation for preventing recurrent VTE in cancer patients. The intervention strategy is Direct Oral AntiCoagulants (DOAC) therapy with edoxaban, apixaban, rivaroxaban, or dabigatran. The comparator is low molecular weight heparin (LMWH) alone or with warfarin. The information gained will empower cancer patients and physicians to make more informed choices about anticoagulation strategies to manage VTE.
Phase:
N/A
Details
Lead Sponsor:
Alliance Foundation Trials, LLC.
Collaborator:
Patient-Centered Outcomes Research Institute
Treatments:
Anticoagulants
Apixaban
Dabigatran
Dalteparin
Edoxaban
Enoxaparin
Fondaparinux
Heparin
Heparin, Low-Molecular-Weight
PENTA
Rivaroxaban
Warfarin