Direct Mechanical Thrombectomy Versus Bridging Therapy

• Status: Completed
• Trial end date: 2020-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study compares the efficacy and safety of direct mechanical thrombectomy versus bridging therapy in patients with anterior circulation large vessel occlusion in a cohort of patients treated at the stroke unit of a single centre at Alexandria University in Egypt.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alexandria University
• Treatments: Plasminogen; Tissue Plasminogen Activator

Criteria

Inclusion Criteria:

• Patients with anterior ischemic stroke due to large vessel occlusion.

• A previous autonomous modified Rankin Scale (mRS) of less than 2.

• A National Institutes of Health Stroke Scale (NIHSS)≥4

• A groin puncture within 4.5 hours of the neurological deficit onset.

Exclusion Criteria:

• Imaging documentation of intracranial haemorrhage

• A premorbid mRS score of 2 or more

• Absence of diffusion perfusion mismatch in CT perfusion.