Dihydroartemisinin-piperaquine and Primaquine for Uncomplicated Plasmodium Falciparum Cases
Status:
Completed
Trial end date:
2010-10-01
Target enrollment:
Participant gender:
Summary
Artemisinin-based combination therapy (ACT) has been known to be controversial for stopping
malaria transmission.The addition of primaquine (PQ) - the only drug commercially available
that kills mature transmission stage - to such treatments might be necessary to eliminate
this stage. A study is conducted to evaluate the efficacy of dihydroartemisinin-piperaquine
(DHP) regimens with or without PQ on the sexual and asexual stages of P. falciparum in
Sumatra, Indonesia.