Digoxin Drug-Drug Interaction With Lurasidone HCl

• Status: Completed
• Trial end date: 2008-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to evaluate the pharmacokinetic profile of digoxin when administered alone and when administered with repeated dose of lurasidone 120mg.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sunovion
• Treatments: Digoxin; Lurasidone Hydrochloride

Criteria

Inclusion Criteria:

• Male and female 18 to 65 years of age

• BMI >= 19.5 and <= 37 kg/m2

• No clinically relevant abnormal laboratory values

Exclusion Criteria:

• History or presence of renal or hepatic insufficiency

• Participated in a clinical trial in the past 30 days

• Use of con meds that prolong the QT/QTc taken within 28 days prior to study drug administration