Different Volatile Anaesthetics and the Depth of Long Term ICU Sedation

• Status: Completed
• Trial end date: 2017-05-31
• Target enrollment: 0
• Participant gender: All

Summary

The MIRUS system (TIM, Andernach, Germany) as well as the AnaConDa uses a reflector to conserve volatile anaesthetics (VA). Both systems can be paired with ICU ventilators, but MIRUS features an automated control of end-tidal VA concentrations (etVA). We compare depth of 0.5 MAC inhalational long-term sedation with Isoflurane (ISO), Sevoflurane (SEVO) or Desflurane (DES).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ruhr University of Bochum
• Treatments: Anesthetics; Desflurane; Isoflurane; Sevoflurane

Criteria

Inclusion Criteria:

• Signing of the informed consent document (patient or relatives).

• Patient age 18 years or older.

• ASA I-III

Exclusion Criteria:

• ASA IV patients

• Epidural or spinal analgesia

• Allergy or known hypersensitivity to any of the study drugs

• Patients with known or suspected genetic susceptibility to malignant hyperthermia

• Previous participation in this trial

• Participation in another clinical trial within 4 weeks prior to selection.

• Pregnant women