Different Methods of Termination of Second Trimester Abortion

• Status: Unknown status
• Trial end date: 2018-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

The Patient are divided into 3 groups group 1 included 50 cases using misoprostol only. group 2 included also 50 cases in which using misoprostol with letrozole. Group3 included also 50 cases in which using misoprostol with Foleys catheter for termination of second trimesteric abortion between 14 and 24 weeks

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Letrozole; Misoprostol

Criteria

Inclusion Criteria:

• singleton pregnancy

• gestational age between 14 and 24 weeks

• Fetal death was confirmed by ultrasonic scan

• Unfavorable cervix using Bishop score for cervical assessment with score less than 5

• Parity less than 5

• No uterine contractions

Exclusion Criteria:

• Previous uterine scar eg scar for cessarian section

• Rupture of membranes

• Chorioamnionitis

• Placenta previa or low lying placenta.

• Women with medical disease like DM, coagulopathy or genital infections.

• Hypersensitivity or contraindications for receiving misoprostol, including:Maternal asthma.Sickle cell disease.Known hypersensitivity to prostaglandins.History of glaucoma