Differences in Malaria Infection Levels in HIV-infected Infants and Children Receiving PI- and NNRTI-based HAART
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
More than 1.5 million deaths of African children under 5 years of age have been due to
Plasmodium falciparum malaria. When HIV and malaria are present as coinfections, they enhance
each other's progression. The primary purpose of this study is to compare the malarial
infection levels in HIV-infected infants and children receiving protease inhibitor (PI)- or
non-nucleotide reverse transcriptase inhibitor (NNRTI)-based highly active antiretroviral
therapy (HAART).
Phase:
Early Phase 1
Details
Lead Sponsor:
International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institute of Allergy and Infectious Diseases (NIAID)