Dietary, Herbal and Alternative Medicine in Glioblastoma Multiforme
Status:
Terminated
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Giving the herb Boswellia serrata after surgery and radiation therapy may slow the
growth of any remaining tumor cells. It is not yet known whether giving Boswellia serrata
together with standard treatment is more effective than standard treatment alone in treating
high-grade gliomas.
PURPOSE: This randomized phase II trial is the study of a combination of complementary and
alternative medicine (CAM) herbal supplement intervention as an adjuvant to standard
treatment of patients with newly diagnosed and recurrent high-grade gliomas (HGG). The
central hypothesis of this application is that a herbal preparation that inhibits 5-LO
activity, will produce measurable biologically meaningful decrease in 5-LO eicosanoid
production and brain edema that will be associated with improved survival and quality of life
in patients with HGG.
Phase:
Phase 2
Details
Lead Sponsor:
Ali Altunkaya
Collaborator:
National Cancer Institute (NCI)
Treatments:
Hydroxocobalamin Vitamin B 12 Vitamin B Complex Vitamins