Overview

Diazoxide Suppression Test P&F Study

Status:
RECRUITING
Trial end date:
2026-01-01
Target enrollment:
Participant gender:
Summary
The goal of this study is to learn about how the hormone insulin controls blood sugar. The main question it aims to answer is about how much insulin the body actually needs to maintain a normal blood sugar level. People with obesity and high insulin levels will receive eight doses of diazoxide, a drug that suppresses the pancreas's production of insulin, and will have their fasting blood sugar and insulin levels checked daily while taking the drug.
Phase:
PHASE1
Details
Lead Sponsor:
Columbia University
Collaborators:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
University of Pisa
Treatments:
Diazoxide