Diagnostic Value of Novel MR Imaging Techniques for the Primary Staging and Restaging of Rectal Cancer

• Status: Completed
• Trial end date: 2016-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the clinical value of the novel MRI-techniques DWI and gadofosveset-enhanced MRI for the management of rectal cancer patients.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maastricht University Medical Center
• Collaborator: Dutch Cancer Society

Criteria

Inclusion Criteria:

• Biopsy proven primary rectal cancer (≤15 cm from the anorectal verge as measured in MRI)

• Age > 18 years

• Written informed consent

Exclusion Criteria:

• Ineligibility to undergo MRI (claustrophobia, pacemaker, non-MR compatible surgical implants, metal fragments in the eye)

• Pregnancy

• Locally recurrent rectal cancer

• A history of severe allergy to contrast agents

• Ineligibility to receive gadofosveset contrast (history of contrast allergy, impaired kidney function with a Glomerular Filtration Rate <30 ml/min/1.73m2

• Incurable disease due to metastases or co-morbidity