Diagnosis of Adenoid Cystic Carcinoma on 68Ga-PSMA-617 PET-CT and Therapy With 177Lu-EB-PSMA-617
Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
Adenoid cystic carcinoma (ACC) accounts for 24% of salivary gland malignant tumors, is
characterized by frequent local recurrences and distant metastasis, mainly to lungs.
Considering its origination from salivary glands, an organ with intense physiological uptake
of 68Ga-PSMA-617, this study aims to evaluate 68Ga-PSMA-617 uptake in local recurrent or
metastatic ACC in comparison with 18F-FDG uptake in the same patients, and assess the
feasibility of 177Lu-EB-PSMA-617 treatment in patients with the advanced ACC.