Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty

• Status: Unknown status
• Trial end date: 2017-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The present study is designed to evaluate and compare the efficacy of intrathecal dexmedetomidine (DEX) as an adjuvant to Levobupivacaine in spinal anaesthesia and DEX's intravenous administration, without loading dose, additionally to spinal anaesthesia, in patients undergoing total knee arthroplasty.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: KAT General Hospital
• Treatments: Anesthetics; Bupivacaine; Levobupivacaine; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Patients selected for total knee arthroplasty of approximately one and half hour (90 min) duration under spinal anaesthesia.

• Patients who belong to American Society of Anaesthesiologists (ASA) physical status grade I and II

Exclusion Criteria:• Patients with coagulation and neurological disorders

• Patients allergic to DEX

• Patients showing unwillingness for spinal anaesthesia