Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and Intubation
Status:
Completed
Trial end date:
2024-01-03
Target enrollment:
Participant gender:
Summary
Laryngoscopy, tracheal intubation, surgical stimulation, and extubation unleash remarkable
sympathetic activity and are associated with transient but significant hemodynamic changes.
The need to blunt these noxious responses effectively has led to using several techniques and
pharmacological agents, local anesthetics, beta-adrenergic-blockers, calcium channel
antagonists, and opioids with varied success. This study aims to evaluate the effect of
nebulized and intravenous either dexmedetomidine or lidocaine for attenuating the hemodynamic
responses to laryngoscopy and intubation.