Dexmedetomidine-ketamine Versus Propofol-ketamine for Sedation During Endoscopy in Hepatic Patients

• Status: Active, not recruiting
• Trial end date: 2021-07-30
• Target enrollment: 0
• Participant gender: All

Summary

We aim to compare the response to ketamine/dexmedetomidine and ketamine/propofol combinations used in hepatic patients with child-Pugh classification (class A), and early (class B) undergoing UGIE.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tamer Nabil Abdelrahman
• Treatments: Dexmedetomidine; Ketamine; Propofol

Criteria

Inclusion Criteria:

• hepatic patients with child-Pugh classification (class A), and (class B)

• American Society of Anesthesiologists physical status II, III

• aged 18 to 60 years

• scheduled for elective Upper gastro-intestinal endoscopy.

Exclusion Criteria:

• emergency gastro-intestinal endoscopy.

• patients with severe hepatic disorder (Child C) ,

• chronic neuro-psychiatric disorder,

• history of neuro-psychiatric drug intake,

• severe cardiovascular diseases,

• pregnancy,

• history of drug abuse, and

• history of allergy to any of the used drugs in the study