Dexmedetomidine in Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy

• Status: Completed
• Trial end date: 2015-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The use of dexmedetomidine as an adjunct to bupivacaine in transversus abdominis plane block will reduce the cumulative morphine consumption after laparoscopic cholecystectomy.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dammam University
• Collaborator: Mansoura University
• Treatments: Bupivacaine; Dexmedetomidine

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists class I and II patients

• general anaesthesia

Exclusion Criteria:

• cardiovascular disease

• respiratory disease

• neurological disease

• renal disease

• hepatic disease

• hormonal disease

• pregnancy

• body mass index > 35 kg/m2)

• smokers

• alcohol abuse

• use of antipsychotics

• communication barriers

• local anesthetics allergy

• chronic use of opioids

• use of nonsteroidal anti-inflammatory drug use during the 24 hours immediately preceding surgery

• coagulation disorders

• infection at the needle insertion

• conversion of laparoscopic to open cholecystectomy