Dexmedetomidine in Children for Magnetic Resonance Imaging (MRI) Sedation

• Status: Completed
• Trial end date: 2014-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Sixty patients aged between 1-10 years, American Society of Anesthesia (ASA) physical status I-II scheduled for MRI were allocated in this randomized double-blinded study. Group 1 received 3 mcg/kg, Group 2 received 4 mcg/kg intranasal dexmedetomidine before imaging. From the beginning on every 10 minutes heart rate (HR), saturation (SpO2) and Ramsey Sedation Score (RSS) were recorded. Induction time was time interval to receive RSS 5. MRI began and separation-score was noted. If intranasal sedation failed, an intravenous canula was placed and propofol was applied. Imaging quality was evaluated. Recovery time was time interval to receive Aldrete-score 9. Parents' satisfaction was questioned before patient was discharged.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sisli Etfal Training & Research Hospital; Sisli Hamidiye Etfal Training and Research Hospital
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• MRI

• ASA I-II

Exclusion Criteria:

• hepatic and renal failure

• difficult airway

• nasal deformity

• anaphylaxis to dexmedetomidine

• neurologic disease

• metabolic disorders

• electrolyte imbalance

• dehydration

• malnutrition