Overview

Dexmedetomidine for the Treatment of Delirium After Heart Surgery

Status:
Terminated
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
Primary hypothesis: Dexmedetomidine is equal or superior to haloperidol and placebo in the treatment of psychomotor confusion in patients who are recovering from heart surgery. Study design: Multi-centre, prospective, randomised, placebo-controlled double-blind study of dexmedetomidine vs. haloperidol for treatment of psychomotor confusion after cardiac surgery. Data will be analyzed in two steps: The primary comparison is between placebo and dexmedetomidine. If the effect of dexmedetomidine is significant, a secondary comparison between dexmedetomidine and haloperidol will follow.
Phase:
Phase 3
Details
Lead Sponsor:
Thorax-Kärlkliniken
Treatments:
Dexmedetomidine
Haloperidol
Haloperidol decanoate