Current cesarean section often chooses spinal anesthesia. And in order to avoid the impact of
drugs on the fetus, before the delivery, anesthesiologist generally don't use sedative or
analgesic drugs. However, the majority of puerperas would appear nervous, anxiety, fear and
other psychological reactions in cesarean section. Although the placental transfer and the
foetal metabolism of dexmedetomidine have been reported and the result show no adverse
effects on neonates, but the placental transfer of dexmedetomidine in intravertebral
anesthesia area was lack of systematical research. This study intends to use of
dexmedetomidine in the cesarean section under epidural anesthesia and investigate its effects
on the parturients' haemodynamics and the neonates' placental transfer and metabolism.
Phase:
Phase 1
Details
Lead Sponsor:
The First Affiliated Hospital with Nanjing Medical University