Dexmedetomidine Versus Sufentanil Plus Ropivacaine for Epidural Labor Analgesia on Neonatal Outcomes
Status:
Not yet recruiting
Trial end date:
2024-05-31
Target enrollment:
Participant gender:
Summary
Sufentanil is commonly used with ropivacaine in epidural labor anesthesia. However, it can
cause some adverse reaction. Dexmedetomidine is an a2-adrenoceptor agonist with high
selectivity, which possesses opioid-sparing and analgesic effects. Published researches have
shown that the ropivacaine combined with dexmedetomidine can effectively relieve
postoperative pain. The purpose of this present study is to compare the effect of ropivacaine
with dexmedetomidine against ropivacaine with sufentanil in epidural labor analgesia on
neonatal outcomes, and also tested the feasibility of a future large randomized trial.