Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy
Status:
Completed
Trial end date:
2021-01-26
Target enrollment:
Participant gender:
Summary
There is no clear consensus among neuroanesthesiologists regarding which anesthetic regimen
is optimal for craniotomy. Propofol and short-acting opioids (such as remifentanil, fentanyl,
or sufentanil) are commonly used. However, use of opioids is associated with increased risk
of respiratory depression and postoperative nausea and vomiting. Dexmedetomidine is a highly
selective α2-adrenoreceptor agonist that has been considered as a useful and safe adjunct to
anesthesia for various surgical procedures