Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell Disease
Status:
Terminated
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
People with sickle cell disease (SCD) may develop acute chest syndrome (ACS), which is a
common and serious lung condition that usually requires hospitalization. Dexamethasone is a
medication that may decrease hospitalization time for people with ACS, but it may also bring
about new sickle cell pain. This study will evaluate the effectiveness of a dexamethasone
regimen that includes a gradual dose reduction at decreasing hospitalization and recovery
time in people with SCD and ACS.