Dexamethasone for Post Traumatic Headache

• Status: Recruiting
• Trial end date: 2023-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a randomized study of intravenous metoclopramide + intravenous dexamethasone versus intravenous metoclopramide for patients with acute post-traumatic headache.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Montefiore Medical Center
• Treatments: Dexamethasone; Metoclopramide

Criteria

Inclusion Criteria:

• Included patients will be adults who meet International Classification of Headache Disorders criteria for acute post-traumatic headache. These are as follows:

• Traumatic injury to the head has occurred

• Headache has developed within 7 days of injury to the head

• Headache is not better accounted for by another diagnosis (eg, migraine or tension-type headache)

• The headache must be rated as moderate or severe in intensity at the time of initial evaluation.

Exclusion Criteria:

• Patients will be excluded if more than ten days have elapsed since the head trauma, if the headache has already been treated with an anti-dopaminergic medication, or for medication allergies or contra-indications including pheochromocytoma, seizure disorder, Parkinson's disease, use of MAO inhibitors, and use of anti-rejection transplant medications.