Dexamethasone for Post Cesarean Delivery Analgesia

• Status: Completed
• Trial end date: 2015-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.

We hypothesize that a single dose of IV dexamethasone administered, as part of a multimodal analgesia after spinal anesthesia will significantly reduce post cesarean delivery opioid consumption and pain

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Iowa
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Morphine

Criteria

Inclusion Criteria:

• English Speaking

• Non-laboring women

• Scheduled Elective Cesarean section under spinal anesthesia

• American Society of Anesthesiologists I-II physical status

Exclusion Criteria:

• Contraindications to spinal anesthesia

• allergy to study medication

• patients with allergy to morphine

• patients with uncontrolled hypertension

• history of peptic ulcer disease

• liver cirrhosis

• diabetes mellitus

• glaucoma

• known IV drug abusers

• patients with chronic pain or on long term opioids

• patients administered steroids in the past week

• women with fetuses having known congenital abnormalities

• psychiatric illness such that they are unable to comprehend or participate in study questions

• patients on antiviral medications or live virus vaccines would also be excluded.