Dexamethasone for Paediatric Adeno-tonsillectomy - A Dose-finding Study
Status:
Terminated
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
Adeno-tonsillectomy is a commonly performed surgical procedure in children. Main morbidities
are postoperative pain, nausea and vomiting, and haemorrhage. Non-steroidal anti-inflammatory
drugs (NSAIDs)widely used for paincontrol increase the risk of postoperative bleeding and
reoperation. Dexamethasone is an powerful antiemetic and has shown analgesic efficacy.
Antiemetic and analgesic dose-response has never been established.