Dexamethasone at Lower Concentration Ropivacaine in the Supraclavicular Nerve Block
Status:
Unknown status
Trial end date:
2020-12-31
Target enrollment:
Participant gender:
Summary
The supraclavicular brachial plexus block is widely used in upper limb surgery below the
shoulder. However, this can easily lead to long-term motor nerve blockage, Horner's syndrome,
phrenic nerve paralysis or systemic poisoning, and even serious side effects such as cardiac
arrest.
Dexamethasone is a synthetic corticosteroid and becoming more common to use steroids as an
adjunct to local anesthetics in brachial plexus block.
In order to reduce the incidence of long-acting topical anesthetics from the nerve block in
the supraclavicular arm, reducing the local anesthetic concentration is a feasible method,
but this will also result in a shorter time to neurological block. The investigators
hypothesized that the addition of Dexamethasone 5 mg to low concentrations (0.25%) of
Ropivacaine would prolong postoperative analgesia.Therefore, the purpose of this study was to
compare the postoperative analgesia and the side effects of postoperative supraclavicular
brachial plexus blockade with the addition of Dexamethasone 5mg to Ropivacaine (0.5%) alone
and Ropivacaine (0.25%) in low concentrations.
Phase:
N/A
Details
Lead Sponsor:
Kaohsiung Medical University Chung-Ho Memorial Hospital