Dexamethasone Intravitreal Implant for the Treatment of Persistent Diabetic Macular Edema
Status:
Completed
Trial end date:
2018-10-24
Target enrollment:
Participant gender:
Summary
Laser photocoagulation and intravitreal anti-vascular growth factor injections are commonly
used treatment options for individuals with diabetic macular edema. However, some patients
continue to experience persistent diabetic macular edema and poor vision despite continued
laser and/or anti-vegf therapy. Recent clinical trials suggest that due to inflammatory
mediators dexamethasone intravitreal implant (0.7mg) may be a good alternative therapy for
individuals unresponsive to laser photocoagulation or intravitreal anti-vascular growth
factor injections. The purpose of this research study is to compare the effectiveness of
using a dexamethasone steroid implant versus monthly intravitreal anti-VEGF injections for
research participants with persistent diabetic macular edema (DME).