Dexamethasone Effect on Pain and Edema Following Mandibular 3rd Molar Surgery; Pre-operatively vs Post-operatively

• Status: Not yet recruiting
• Trial end date: 2020-11-01
• Target enrollment: 0
• Participant gender: All

Summary

TThis is a comparative clinical study which will be conducted in OMFS department of DIKIOHS, DUHS Ojha Karachi. In this study the investigators will be comparing the effect of dexamethasone on pain and edema when administered pre-operatively vs post-operatively following surgery of impacted lower 3rd molars. Time duration of this study will be 2 months. A total of 100 patients will be considered in this study which will be equally divided into two groups; group A and group B (50 in each group).Group A will receive dexamethasone 1 hour pre-operatively while group B will receive the same post-operatively. All surgeries will be performed by the same maxillofacial surgeon and duration of surgery will be around 30-45 mins.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Dow University of Health Sciences
• Treatments: BB 1101; Dexamethasone; Dexamethasone acetate

Criteria

Inclusion Criteria:

• Patients coming to dental OPD of DIKIOHS, DUHS, Ojha with Mesioangular impactions

• Age of patients: 20-50 years

Exclusion Criteria:

• Patients with known co-morbidities

• Patients allergic to dexamethasone

• Patients with history of recent anti-inflammatory drug intake(NSAIDs, steroids, or antihistamines)

• Pregnant/lactating females