Dexamethasone Compared With Dexmedetomidine as an Adjuvant to Ropivacaine for Supraclavicular Brachial Plexus Block

• Status: Completed
• Trial end date: 2018-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators want to compare the effectiveness of dexamethasone and dexmedetomidine as an adjuvant to 0.5% ropivacaine for supraclavicular brachial plexus block on the onset of block and duration of analgesia, so that the investigators can choose the better adjuvant for the investigators routine practice of regional anesthesia.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: B.P. Koirala Institute of Health Sciences
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Dexmedetomidine; Ropivacaine

Criteria

Inclusion Criteria:

• Patients of American Society of Anesthesiologists Physical Status I and II undergoing elective upper limb surgery under supraclavicular brachial plexus block

Exclusion Criteria:

• Patient's refusal to participate

• Patients weighing less than 40 kg

• Allergy to study drugs

• Infection at the site of injection

• Patients with preexisting neurological deficit

• Patients with diabetes mellitus

• Patients on steroids preoperatively

• Patients with bleeding disorder or coagulopathy

• Abnormalities in ECG like AV block or symptomatic bradycardia

• Patients receiving adrenoreceptor agonist or antagonist therapy preoperatively

• Requirement of conversion to general anesthesia due to inadequate block