Overview

Developing ctDNA Guided Adjuvant Therapy for Gastrooesophageal Cancer

Status:
Recruiting
Trial end date:
2028-04-30
Target enrollment:
Participant gender:
Summary
Multicentre, single arm, open label UK phase II trial to assess the efficacy of trastuzumab deruxtecan in reducing micrometastatic disease burden in HER2 positive GOA patients who are ctDNA positive after chemotherapy and surgery. 25 patients will be recruited from approximately 15 NHS secondary care sites.
Phase:
Phase 2
Details
Lead Sponsor:
University of Southampton
Collaborators:
AstraZeneca
Natera, Inc.
Treatments:
Trastuzumab
Trastuzumab deruxtecan