Overview

Developing Oral LT3 Therapy for Heart Failure - HFpEF

Status:
Recruiting
Trial end date:
2023-04-30
Target enrollment:
Participant gender:
Summary
Investigation of the safety, feasibility, and preliminary efficacy of thyroid hormone therapy with Liothyronine (LT3) in individuals with heart failure with preserved ejection fraction (HFpEF) and low triiodothyronine (T3) syndrome by conducting a randomized, double-blind, placebo-controlled cross-over study with a two-week washout period between treatments.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
University of Pennsylvania
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)