Determining Optimal Dose and Duration of Diuretic Treatment in People With Acute Heart Failure (The DOSE-AHF Study)
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
Heart failure is a disorder in which the heart does not pump blood adequately. This can lead
to several serious problems, including reduced blood flow throughout the body, congestion of
blood in the veins and lungs, and fluid accumulation in various organs and limbs. Diuretics
are often used to address the problem of fluid accumulation, but the optimal dose and the
amount of time over which to administer each dose are unclear. This study will compare high
and low doses of diuretics administered over longer and shorter periods of time to determine
the safest and most effective combination.