Overview

Detection of Diffuse Scar in Patients With Diabetes

Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
People with diabetes are at an increased risk of heart attacks and heart failure, and it is important to be able to treat people with diabetes who are at risk for heart disease to prevent these outcomes. This study is looking at the importance of "diffuse scar tissue" that is found in the heart of diabetic people. We have discovered a way to detect diffuse scar tissue by cardiac MRI, a non-invasive test. In this study, we do cardiac MRI on diabetics with low risk stress test results and follow them for 5 years to see if the measure of scar tissue in the heart by MRI is related to events. If this study is positive, we will be able to use cardiac MRI scar tissue measurements to target those patients with diabetes who are at highest risk.
Phase:
Phase 1
Details
Lead Sponsor:
Brigham and Women's Hospital
Treatments:
Eplerenone
Spironolactone