Desogestrel for the Preoperative Treatment of Endometrioma Compared With Placebo

• Status: Recruiting
• Trial end date: 2022-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Use of the oral desogestrel compared with placebo for preoperative treatment of endometrioma in the patient who underwent to surgery in next 3 months The result will be evaluated on cyst diameter, the associated pain and side effect of the oral desogestrel.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Rajavithi Hospital
• Treatments: Desogestrel

Criteria

Inclusion Criteria:

• Thai female and foreigner who can understand Thai language

• Age 15-49 years

• Diagnose as endometrioma sized more than 3 cm

• Underwent to surgery in next 13 weeks

Exclusion Criteria:

• History of endometriosis

• Pregnancy woman

• Contraindication for desogestrel : History of thrombotic event, Autoimmune disease,gestational trophoblastic disease

• Ovarian endometrioma with complications : Ruptured, twisted

• Contraindications for NSAIDs : Peptic ulcer, thrombocytopenia, liver disease

• History of hormonal treatment for endometrioma : DMPA,OCP, GNRH agonist/antoginist