Desmopressin for Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Bladder Reconstruction

• Status: Unknown status
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to prospectively assess whether Desmopressin, given for a period of month to patients after radical cystectomy with orthotopic bladder reconstruction, improves and lowers the rate of nocturnal enuresis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rabin Medical Center
• Treatments: Deamino Arginine Vasopressin

Criteria

Inclusion Criteria:

• Age above 18

• Able to give informed consent

• Patients afte radical cystectomy with orthotopic bladder reconstruction with night time incontinence

Exclusion Criteria:

• Patients with after radical cystectomy with orthotopic bladder reconstruction with daytime urinary incontinence

• Patients already treated with Desmopressin due to other reasons.

• Patients with an allergy or insensitivity to Desmopressin.

• Patients with known hyponatremia

• Patients with severe chronic renal failure and creatinine clearance of below 50 cc/sec.

• Patients with severe congestive heart failure

• Patients with active urinary tract infection

• Patients taking drug therapy which can interact with Desmopressin and affect it's action.Examples include Diuretics, Tricyclic antidepressants, Carbamezapine and Chlorpropamide AND Indomethacin.

• Patients with an indwelling urinary catheter.