Desmopressin and Dexamethasone Adjunctive Treatment for Leptospirosis
Status:
Terminated
Trial end date:
2006-10-01
Target enrollment:
Participant gender:
Summary
Background: Pulmonary involvement in leptospirosis has been reported to be on the increase
and is emerging as the main cause of death due to leptospirosis in many countries, including
Thailand.
Methods: A prospective randomized controlled trial of desmopressin or high dose dexamethasone
as adjunctive therapy in patients with suspected pulmonary hemorrhage associated with
leptospirosis was conducted between July 2003 and October 2006 at 5 hospitals in Thailand.