Depth of Botulinum Neurotoxin Injection for Treatment of Glabellar Lines
Status:
Not yet recruiting
Trial end date:
2023-12-01
Target enrollment:
Participant gender:
Summary
STUDY QUESTION: Does the depth of injection of onabotulinumtoxinA neurotoxin in the glabellar
complex affect efficacy of the BoTN for the improvement of glabellar frown lines? STUDY AIM
- Primary objective: Compare the efficacy of onabotulinumtoxinA neurotoxin injected at the
depth of 2mm vs 4mm for the improvement of glabellar lines
- Secondary objective: Determine any adverse effects of onabotulinumtoxinA neurotoxin
injected at the depth of 2mm vs 4mm
RATIONALE FOR THE PROJECT:
Although the use of BoTN for treatment of glabellar lines has long been established as safe
and effective, the optimal depth of injection has not been established. Our project hopes to
establish the optimal depth of injection for onabotulinumtoxinA neurotoxin for maximal
improvement of glabellar lines with minimal adverse effects