Depression in Alzheimer's Disease-2

• Status: Completed
• Trial end date: 2009-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to learn whether treating individuals with Alzheimer's disease and depression with the anti-depressant medication sertraline (Zoloft) is helpful to people with Alzheimer's disease and to their families and caregivers.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johns Hopkins University
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Sertraline

Criteria

Inclusion:

• Ability of the participant, caregiver or surrogate to provide written informed consent.

• Dementia due to Alzheimer's disease

• Stable treatment for Alzheimer's disease

• Ability for the participant's caregiver to accompany the participant to study visits and participate in the study.

Exclusion

• Presence of a brain disease that might otherwise explain the presence of dementia

• Clinically significant hallucinations or delusions

• Current treatment of antipsychotics, anticonvulsants, and other antidepressants, benzodiazepines, or other psychotropic medications

• Need for hospitalization or residence in a nursing facility