Overview

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis

Status:
Terminated
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
Objectives: - To determine the safety, tolerability and maximum tolerated dose (MTD) of oral temozolomide using a 7 days on and 7 days off regimen combined with intrathecal liposomal cytarabine (DepoCyt) in patients with neoplastic meningitis from solid tumors and systemic lymphoma.
Phase:
Phase 1
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborators:
Enzon Pharmaceuticals, Inc.
Schering-Plough
Treatments:
Cytarabine
Dacarbazine
Temozolomide