Overview

Denosumab Safety Assessment in Multiple Observational Databases

Status:
Active, not recruiting
Trial end date:
2024-08-14
Target enrollment:
Participant gender:
Summary
This is a prospective open-cohort study with annual assessment and reporting of descriptive findings from 5 secondary data sources. The study period will include up to 10 years in each data system. The secondary data sources will be the following: *US Medicare, including Parts A, B, and D* United HealthCare* Scandinavian national health registry databases, including data from Denmark, Sweden, and Norway. Data will be collected for postmenopausal women overall, women with PMO, and patients who receive Prolia for unapproved indications.
Details
Lead Sponsor:
Amgen
Collaborators:
Aarhus University Hospital
OPTUM Insight
Optum, Inc.
University of Alabama at Birmingham
Treatments:
Denosumab
Diphosphonates