Denosumab Effect on Bone Quality and Function After Lumbar Fusion Surgery
Status:
Recruiting
Trial end date:
2022-06-15
Target enrollment:
Participant gender:
Summary
Degenerative lumbar spinal diseases have become a common health problem and the most frequent
indication for spinal surgery in elderly individuals . It mainly contain lumbar spinal
stenosis and spondylolisthesis, manifested as a series of lumbago, leg pain and neurological
symptoms and compressed the dural sac or nerve root. Lumbar spinal stenosis and
spondylolisthesis occurs in most people over 60 years of age, and patients primarily
diagnosed with lumbar degenerative disease are more likely to have osteoporosis. Our study
was to explore denosumab effect on bone quality and function status in osteopenia and
osteoporosis patients with lumbar degenerative diseases after lumbar fusion surgery